When it comes to designing a beautiful bedroom for guests, comfort is key. A guest room should be a welcoming space that combines the amenities of a hotel with the intimacy and charm of a home. To create an inviting design, consider the essentials for any road-weary traveler: a luxurious bed, a chair for reading or making phone calls, and those frequently forgotten items such as phone chargers and toiletries. The guest room is also the perfect spot to experiment with decor trends that you like but might not want to live with every day in your own bedroom—think bold wall treatments, bright colors, and twin beds . These gorgeous spaces from the AD archives offer decor ideas from top designers including Miles Redd, Sig Bergamin, and Anouska Hempel. Create a room like one of these and your visitors won’t ever want to leave.

In the guest room of a Bridgehampton, New York, home decorated by the Steven Gambrel, overscale 1960s table lamps flank a Gambrel-designed bed dressed with Pottery Barn sheets. The vintage rattan mirrors came from a Paris flea market.

At photographer and antiques dealer Matthias Vriens-McGrath’s Los Angeles house , a guest room features a Directoire wrought-iron bed draped in antique toile; an angora tulu rug covers the bench.

A walnut-paneled guest room in Alex Rodriguez's Briggs Edward Solomon–designed Florida home displays a large Adam McEwen work; the wall light is by Flos, and the Warren Platner side tables are by Knoll.

A guest room in a São Paulo residence designed by Sig Bergamin features walls decorated by Nathalie Morhange, Victoria Mill bed linens, and Arraiolos carpets; the armchair is upholstered in a Romo cotton-linen.

In the guest room of a Southampton, New York, retreat designed by David Netto, the Le Manach cotton on the walls and headboard and Rosa Bernal Collection fabric used for the pillow shams are both from Claremont; a Rose Tarlow Melrose House table lamp perches on a mahogany nightstand from Sutter Antiques.

In architect Steve Mensch's house above the Hudson River , near Rhinebeck, New York, an African sculpture and an Adesso lamp keep watch over a guest room’s Modloft bed, which is dressed in a Room & Board wool blanket. The Mies van der Rohe chair is vintage, the side table is by B&B Italia, and the rug is by Calvin Klein Home.

The Green Bedroom, a guest room in a Marrakech riad, is appointed with a 19th-century Persian light and a bone-inlay-embellished desk and chair.

American-oak beams crisscross the ceiling in a top-floor guest room of designer Anouska Hempel’s manor home in Wiltshire, England.

In Sig Bergamin’s São Paulo home, a brilliant ikat envelops the guest room, where the headboard upholstery and curtain fabric are both by Kravet; the luggage is vintage Louis Vuitton.

In Ray Booth and John Shea’s Nashville, Tennessee, home, a guest room features a Groundworks wallpaper from Lee Jofa and a custom-made bed.

Peter Rogers employed a pair of Regency beds in the guest room of his New Orleans home, along with an antique Swedish gilded stool.

A guest room in a Martha’s Vineyard, Massachusetts, home is outfitted with twin beds designed by Mark Cunningham; the curtains are of a Robert Kime fabric from John Rosselli & Assoc. and were made by Anthony Lawrence-Belfair.

A Hamptons guest room designed by Foley & Cox is appointed with a Blu Dot bed and a glass-top trestle table by Richard Wrightman Design; the floor lamp is by Isamu Noguchi.

A plethora of patterns enlivens a guest room in a Connecticut home designed by Miles Redd, from a Farrow & Ball wallpaper to a vintage fabric on the Louis XVI settee and chair.

In a bamboo-themed Florida guest room by John Stefanidis, a Regency bed has curtains of white linen trimmed with grosgrain ribbon; the walls are stenciled with a motif taken from a Stefanidis-designed fabric used in an adjacent sitting room, and a kilim covers the floor.

Modeled after the work of Alexander Calder, a Rio de Janeiro guest room’s maguey-fiber wall hanging was handwoven in Central America in the 1970s; the bed, created by the homeowner, the late interior designer Alberto Pinto, is upholstered in a mix of leather and fabric.

In the guest room of a New Orleans home designed by Lee Ledbetter, the bedside tables are vintage Paul McCobb, and the Louis XVI–style bench is clad in a Pollack velvet.

A circa-1840 New England bed anchors the Charleston, South Carolina–inspired guest room in Andrea Anson’s New York townhouse.

Murals of fantastical plants ornament a Florida guest room designed by Nancy Morton.

In Knoll CEO Andrew Cogan’s Shelter Island, New York, home, a guest room is furnished with a 1950s Italian bed and a ’60s Scandinavian dresser.

In a handsome Chicago prewar apartment designed by Jean-Louis Deniot, guests slumber in a statement-making bed designed by Phyllis Morris in the 1970s.